Cancer Research UK Beatson Institute

Identifying biomarkers and therapeutic targets in primary breast angiosarcoma using iPSC-derived endothelial models

Explore how co-occurring mutations in PIK3CA and KDR drive rare primary breast angiosarcoma using innovative iPSC-derived endothelial models. Generate new insights into tumor initiation, identify biomarkers, and test ta…

This research addresses critical gaps in understanding primary breast angiosarcoma, a rare and lethal cancer with poor prognosis and few tr…

Identifying biomarkers and therapeutic targets in primary breast angiosarcoma using iPSC-derived endothelial models

Develop innovative iPSC-derived models of primary breast angiosarcoma to uncover novel biomarkers and therapeutic targets. Apply cutting-edge multi-omics and drug screening to propel advancements in rare cancer treatmen…

This research addresses critical gaps in understanding primary breast angiosarcoma, a rare and deadly disease. Insights gained will enable …