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🎓 Cancer Biology PhDs

Mechanistic Insights into How KMT2D Controls Transcription, DNA Repair and Genome Stability
Aston University Dr Theo Kantidakis 🎓 Cancer Biology 🎓 Molecular Biology

Explore how KMT2D mutations contribute to cancer and developmental disorders by dissecting its role in transcription and DNA repair. Use cutting-edge genomic techniques to differentiate catalytic and non-catalytic tumor…

This research addresses crucial gaps in understanding how KMT2D mutations drive cancer progression and developmental syndromes like Kabuki …

1470+ citations · h14
Gene expression mRNA tRNA chromatin
Develop and Validate Blood-Borne Lung Cancer Diagnostic Biomarkers Using Multi-Omics and Interpretable AI
University of Liverpool Dr Tao You 🎓 Applied Mathematics 🎓 Bioinformatics

Explore blood-borne biomarkers for early lung cancer detection using matched proteomic, miRNA, and metabolomic data. Integrate multi-omics with novel network and survival models to uncover early disease signals.

This research has the potential to revolutionize lung cancer detection by identifying biomarkers detectable years before clinical diagnosis…

595+ citations · h10
Systems Medicine Pharmacometrics Quantitative Systems Pharmacology
Identifying biomarkers and therapeutic targets in primary breast angiosarcoma using iPSC-derived endothelial models
Cancer Research UK Beatson Institute Dr Ralitsa Madsen 🎓 Cancer Biology 🎓 Cell Biology

Explore how co-occurring mutations in PIK3CA and KDR drive rare primary breast angiosarcoma using innovative iPSC-derived endothelial models. Generate new insights into tumor initiation, identify biomarkers, and test ta…

This research addresses critical gaps in understanding primary breast angiosarcoma, a rare and lethal cancer with poor prognosis and few tr…

567+ citations · h5
Primary Breast Angiosarcoma PIK3CA Mutations KDR Mutations iPSC-Endothelial Models
Tumour-microplastic interaction and their role in tumour growth kinetics
Monash University Malaysia Dr Ean Hin Ooi 🎓 Biomedical Engineering 🎓 Cancer Biology

Explore how microplastics influence tumour growth by combining laboratory experiments and computational simulations. Investigate their role in altering tumour mechanics to impact cancer progression.

This research uncovers the effects of environmental microplastics in cancer biology, potentially influencing cancer initiation and progress…

2902+ citations · h30
Computational modelling biomedical engineering medical devices