Synergistic Acoustic-Electrostatic-Inertial Separation of Microplastics from Blood
Explore novel methods to separate microplastics from blood using acoustics and electrostatic forces. Develop clinically relevant devices leveraging multidisciplinary engineering techniques.
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Project Description
Project Overview
Microplastics in blood pose significant health risks including cerebral thrombosis, endothelial dysfunction, cardiovascular disease progression, and systemic inflammation. Current bulk filtering methods for microplastic separation are inefficient clinically. This project develops advanced separation strategies using surface acoustic waves, functionalized surfaces exploiting electromechanical properties of microplastics, and hydrodynamic forces based on particle size and mass differences.
What You Will Do
Investigate synergistic effects of acoustic, electrostatic, and inertial forces for efficient microplastic separation from blood. Conduct experiments involving surface acoustic waves, interdigital transducers, 3D printing, and microfluidic device fabrication. Collaborate with multidisciplinary teams to optimize device concepts targeting clinical applicability.
Expected Outcomes
This research aims to create novel devices capable of effectively isolating microplastics in blood samples with improved efficiency and clinical feasibility. Findings will support the development of interventions to reduce microplastic-induced health risks.
Why This Matters
Microplastics exposure is an emerging public health concern with links to severe cardiovascular and systemic conditions. Developing effective separation techniques is critical to advancing clinically viable treatments and improving patient outcomes by minimizing microplastic contamination in blood.
Entry Requirements
How to Apply
Eligibility
Supervisor Profile
Dr Ajay Achath Mohanan specializes in surface acoustic wave sensor technologies and microfabrication methods. His work involves the development and optimization of acoustic wave-based sensors using novel materials such as ZnO nanowires. He is an active researcher in acoustics engineering and sensor development with a focus on biomedical applications, evidenced by his numerous publications in sensor and materials journals.