Optimising Creatine Dosing Strategies for Brain Health in Mild Traumatic Brain Injury
Investigate how creatine dosing affects brain health after mild traumatic brain injury. Utilize human trials and advanced brain imaging to discover effective supplementation strategies that could improve clinical outcomes and athletic recovery.
AI-generated overview
Project Description
Project Overview
This research focuses on optimising creatine monohydrate dosing strategies to support brain health, particularly following mild traumatic brain injury (mTBI). Creatine plays a crucial role in brain energy metabolism, but optimal dosing, timing, and duration for brain benefits remain unclear. The project will explore how these factors influence brain creatine availability and markers of brain function and recovery.
What You Will Do
You will design and conduct human trials, utilize advanced brain imaging techniques, and perform cognitive assessments to examine the effects of creatine supplementation. Expertise in experimental design, clinical research methods, and data analysis will be developed. Collaboration across neuroscience, nutrition, and sports medicine fields will be integral, supported by access to state-of-the-art laboratories.
Expected Outcomes
The project aims to generate evidence-based guidelines for creatine dosing strategies to improve brain recovery after mTBI. Findings could directly impact clinical practice and sport-specific nutritional recommendations, benefiting both athletic and non-athletic populations affected by brain injury.
Why This Matters
Understanding how to optimise creatine supplementation addresses a significant gap in brain injury recovery strategies. By advancing knowledge of nutritional approaches to brain energy metabolism after mTBI, this research has potential to enhance recovery outcomes and quality of life for many.
Entry Requirements
How to Apply
Eligibility
Supervisor Profile
Prof Craig Sale is a researcher affiliated with Manchester Metropolitan University, with expertise spanning neuroscience, nutrition, and sports medicine. His work focuses on muscle and brain metabolism, including dietary supplementation effects on human performance and recovery. He is well-published and recognized for his contributions to exercise physiology and brain health research.