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🎓 Nursing & Health PhDs

Nanoscale Additive Manufacturing of Buccal Microneedle Patches for Enhanced Trans-Mucosal Drug Transport
Aston University Dr C Russell 🎓 Nursing & Health

Explore nanoscale additive manufacturing to develop microneedle patches for improved buccal drug delivery. Investigate optimized geometries and encapsulation techniques to enhance trans-mucosal transport of therapeutics…

This research addresses critical challenges in non-invasive drug administration by enhancing the efficiency and reliability of buccal drug …

306+ citations · h9
Pharmaceutical Science Physiology Pharmacology Medicines Research
Retention of Dry Eye Disease Management Formulations in the Eye
Aston University Dr Debarun Dutta 🎓 Health Sciences 🎓 Nursing & Health

Explore the retention of ocular lubricants in dry eye disease treatment using innovative fluorophotometry. Develop clinical tools and lead trials to advance anterior eye research and improve therapeutic outcomes.

This research addresses a common and impactful eye condition affecting millions globally, aiming to optimize treatment formulations and mon…

3251+ citations · h30
cornea contact lens ocular surface
Antimicrobial Resistance and Gene Regulation in Enteroaggregative Escherichia coli
Aston University Dr Douglas Browning 🎓 Nursing & Health

Explore how a novel AggR variant controls virulence in antibiotic-resistant EAEC strains. Use genome analysis and synthetic biology to develop potential new therapies against EAEC infections.

This research addresses antimicrobial resistance in a globally significant pathogen causing diarrhoeal disease, especially in vulnerable po…

6405+ citations · h36
Bacterial gene expression Recombinant Protein Production Bacterial chromosome structure Outer membrane biogenesis in Gram-neg
Development of antioxidant-loaded dermal formulations for diabetic wound healing
Aston University Dr. Mandeep Marwah 🎓 Nursing & Health

Investigate the development of antioxidant-loaded dermal gels to improve healing in diabetic wounds. Develop novel biomaterials and validate efficacy in a 3D diabetic wound model mimicking inflammatory conditions. Explo…

This research addresses the critical challenge of poor healing in diabetic wounds, a condition that affects millions and often leads to sev…

383+ citations · h13
Diabetic Wounds Antioxidant Therapy Angiogenesis Dermal Formulations
Exploring Cultural and Social Influences on ADHD Medication Choices in Diverse Communities
Aston University Dr Muhammad Umair Khan 🎓 Nursing & Health

Explore how cultural and social factors affect ADHD medication choices in ethnic minority communities. Use qualitative and quantitative methods to reveal barriers and support equitable care. Inform culturally sensitive …

This research addresses critical inequities in ADHD treatment by uncovering how cultural and social contexts shape medication decisions. Un…

2892+ citations · h29
Medicines optimisation mental health medication decision-making ADHD
Regulation of brain fluid homeostasis by dynamic aquaporin-4 subcellular relocalisation
Aston University Dr Philip Kitchen 🎓 Nursing & Health

Explore how aquaporin-4 localization controls brain water balance using cutting-edge methods. Aim to uncover mechanisms linking water transport regulation to neurodegeneration and brain swelling, offering pathways to ne…

Understanding aquaporin-4 regulation is crucial to controlling brain water balance and edema, which are key factors in stroke, traumatic in…

3732+ citations · h26
Aquaporin-4 Brain Water Homeostasis Neurodegeneration Glymphatic Function
Mechanistic Insights into How KMT2D Controls Transcription, DNA Repair and Genome Stability
Aston University Dr Theo Kantidakis 🎓 Cancer Biology 🎓 Molecular Biology

Explore how KMT2D mutations contribute to cancer and developmental disorders by dissecting its role in transcription and DNA repair. Use cutting-edge genomic techniques to differentiate catalytic and non-catalytic tumor…

This research addresses crucial gaps in understanding how KMT2D mutations drive cancer progression and developmental syndromes like Kabuki …

1470+ citations · h14
Gene expression mRNA tRNA chromatin
GTP Depletion and Genome Stability: Mechanistic Insights into Mycophenolic Acid-Induced Transcriptional and DNA Damage Responses
Aston University Dr Theo Kantidakis 🎓 Genetics 🎓 Molecular Biology

Explore how metabolic stress from mycophenolic acid affects genome stability and transcription. Investigate DNA repair and chromatin changes with direct relevance to cancer and transplant medicine. Employ molecular biol…

This research reveals broader effects of a widely prescribed immunosuppressant on genome stability, challenging assumptions about its selec…

1470+ citations · h14
Gene expression mRNA tRNA chromatin
Deciphering Stress Response in Healthy Aging
Aston University Dr Zita Balklava 🎓 Nursing & Health

Explore how stress granule dynamics change with age and affect organismal aging using C. elegans. Investigate molecular and physiological aging markers and stress recovery to understand mechanisms promoting healthy agin…

This research addresses critical gaps in understanding the cellular mechanisms linking stress responses to aging. By uncovering how stress …

Stress Granules Healthy Aging Proteostasis Oxidative Stress
Review and Evaluation of Mobile Technology to Reduce Medication Burden in Older People
Aston University Prof Ian Maidment 🎓 Nursing & Health

Explore how mobile technology can ease medication burden for older adults. Conduct realist reviews and interviews to develop policies and technology designs that improve medication management in aging populations.

This research addresses the critical challenge of polypharmacy in older adults, a growing issue that complicates health management and incr…

8044+ citations · h41
Medication Management Mental Health Dementia